The checklist in this book was constructed from a wide variety of published sources and experience of working at local, national and international levels to perform research ethics review for a range of agencies. It was primarily designed for social science research ethics review, but can easily be applied or amended for any proposed scientific research. It can be used as an aide memoire, as a guide to ethical assurance for contracting parties, and as the basis for an ethical scrutiny protocol for research projects conducted by any individual researcher, research group or commissioning body. Completing this form is designed to help in ‘thinking through’ and anticipating harms and benefits at the outset of a project, but also to support ongoing monitoring of such concerns throughout the life of a project. Use tick boxes to show decisions taken and fill in comment sections briefly to record rationales for decisions. If a fuller comment is required to explain the rationale for a decision then it is suggested to append parallel sheets.