The overall goal of the PRO-RES project is to build a research ethics and integrity framework devised cooperatively with, and seen as acceptable by, the full range of relevant stakeholders and similar to Oviedo/Helsinki guidance frameworks in the medical fields. PRO-RES will draw upon previous foundational work funded by the EC, and other national and international agencies. To be durable and sustainable, the outcome must also be flexible enough to meet anticipated future needs. It is also essential to ensure that the Framework incorporates RRI principles and practices, especially regarding the governance of RRI. Consequently, the framework will be ‘staged’ starting with a simple introductory level of ‘basic principles’ leading to more explanatory/background levels and ultimately more complex aids for decision-making at later stages.